Cubs starter Edward Cabrera gives up eight runs, doesn’t get out of fourth inning in return from injury

For one painful afternoon Friday at Wrigley Field, Cubs right-hander Edward Cabrera earned a new nickname: ‘‘El Aguafiesta.’’ Loosely translated, that’s Spanish for buzzkill.

Cabrera hadn’t pitched since May 20 because of a blister on the middle finger of his pitching hand.

This was not independently confirmed, but many in the crowd of 39,060 left with blisters on their derrieres Friday from all the squirming they did while watching seven Giants blasts leave the yard in an 18-3 demolition of the home nine.

So much for any positive carryover from the Cubs’ ninth-inning comeback victory Thursday against the Athletics, which inspired team icon Anthony Rizzo, sitting in a front-row field box, to tear off his shirt, “Tarps Off”-style. Rizzo was not front and center Friday. But if he had been, he might have been inclined to wear a bag over his head.

Wrigley organist Josh Langhoff played a few bars of the ‘‘Hallelujah Chorus’’ when the skies parted, the rain stopped and play commenced after an hour delay. Had he known what was coming, Langhoff might have switched to country mode and played Patsy Cline’s ‘‘I Fall to Pieces.’’

That chorus line of happy Cubs high-stepping across home plate four times in the ninth inning Thursday was replaced by a shell-shocked parade of Cubs pitchers Friday afternoon that started with Cabrera. He allowed eight runs and eight hits, including three home runs, and didn’t survive a fourth inning in which he gave up a grand slam to Matt Chapman and, three batters later, a two-run shot to Casey Schmitt.

‘‘The stuff, I thought, kind of ticked up from where we left it before he went on the injured list,’’ manager Craig Counsell said. ‘‘He just made some bad pitches, and they put them in the seats.’’

Almost inconceivably, it didn’t get any better after Cabrera departed. The Giants, who began hitting almost from the time they got off the bus — Luis Arraez doubled and Willy Adames hit the first of his two homers for a 2-0 lead four batters into the game — didn’t stop until the blue ‘‘L’’ flag was hanging above the scoreboard.

The Giants sent 10 batters to the plate in their six-run fourth. They sent another dozen batters to the plate in their seven-run, eight-hit sixth, which included the second homers of the game for Adames (two-run shot) and Chapman (three-run shot).

Adames’ second homer came against lefty reliever Hoby Milner, who entered the game with a 2.28 ERA, a reflection of how well he has performed this season, and left with an inflated 4.18 ERA, which is what happens to a reliever when he gives up six runs in a third of an inning. Ethan Roberts replaced the forlorn Milner after a hit batsman and single and gave up the second homer to Chapman, the first batter he faced.

By that point, the score was 16-nil, but the crowd was so benumbed that most folks couldn’t be bothered to boo.

Chapman, who also hit a sacrifice fly in the fifth against Phil Maton, finished with eight RBI, a career high, tying a San Francisco record. It was also the most RBI by a player in the majors this season.

Hall of Fame right-hander Fergie Jenkins was in the house — he led the singing of ‘‘Take Me Out to the Ball Game’’ — but Fergie is 83. When it was time to summon someone to pitch the ninth, Counsell opted for a catcher, Carson Kelly.

Kelly’s first pitch of the ninth registered 61.7 mph on the radar gun. Jonah Cox hit it 446 feet, with substitute center fielder Kevin Alcantara giving it a half-wave as it disappeared into the center-field bleachers.

Kelly’s second pitch came in at 49.7 mph. Schmitt hit it 424 feet into the bleachers in left-center.

Kelly set down the next three Giants in order, on two pop-ups and a comebacker to the mound. That, in itself, was worthy of a standing ‘‘O,’’ but most folks by then had headed to the exits.