Liverpool will face Tottenham at home in the third round of the Carabao Cup.
The tie will see Andrew Robertson make a quick return to Anfield following his summer move to Spurs.
There are four other definite all-Premier League ties with Manchester United at home to Brighton, who won at Old Trafford in the FA Cup third-round last season.
Sunderland entertain Hull, Ipswich welcome Premier League champions Arsenal to Portman Road and Aston Villa make the short trip to Coventry.
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Chelsea will welcome to Leeds to Stamford Bridge in another top-flight tie should they beat Luton in Thursday’s second-round clash.
Holders Manchester City are home to Norwich and Bournemouth and Crystal Palace also host Championship opposition with respective ties against Lincoln and Middlesbrough.
Newcastle face a tough looking trip to in-form Millwall, Everton entertain Wolves and West Ham will be at home to the winners of Fulham or Wimbledon.
Brentford make the short trip to Reading, while the remaining ties see Sheffield United at Fleetwood, Leyton Orient at home to Bradford and Peterborough meeting Barnsley.
Ties will be played in the weeks commencing September 7 and 14.
Roberto De Zerbi, meanwhile, toasted the perfect day for Tottenham new boy Savio but then ordered him to hit doubles figures this season.
Spurs completed the £85million signing of Savio from Manchester City on Tuesday to bring a lengthy pursuit to a satisfactory conclusion and the 22-year-old quickly made himself a hit with fans in a 5-1 thrashing of Charlton in the Carabao Cup.
Savio was introduced in the 71st minute and got off the mark for his new club with 82 minutes on the clock with a fizzing low effort into the bottom corner before a side-footed shot three minutes later was deflected in by Ben Davies to round off Tottenham’s scoring.
Carabao Cup third round draw
Crystal Palace v Middlesbrough
Manchester United v Brighton
Manchester City v Norwich
Sunderland v Hull
Ipswich v Arsenal
Coventry v Aston Villa
Bournemouth v Lincoln
Liverpool v Tottenham
Chelsea/Luton v Leeds
Millwall v Newcastle
Fleetwood v Sheffield United
Everton v Wolves
Leyton Orient v Bradford
Reading v Brentford
Peterborough v Barnsley
West Ham v Fulham/AFC Wimbledon
‘Yes, it is a perfect day for him,’ De Zerbi said of Savio.
‘I think his biggest step and biggest improvement is to increase the number of goals because as qualities, I think he is one of the best wingers, but the best wingers score many goals.
‘I spoke with him and we put the goal on 10 or 12 goals (target) because we need 10 or 12 goals from the wingers.
‘Last season we suffered too much because also the number of goals were not enough to compete for nothing more than that (17th) position.’