Palace are looking to move back inside the top four with an away win at Craven Cottage against Marco Silva’s side.
However, Oliver Glasner’s side were dealt a major blow before kick-off after Munoz was ruled out of the clash due to a knee injury.
The Colombian wing-back has been ever-present for the Eagles in the league so far this campaign, and scored the winner in their 1-0 win over Burnley in midweek.
Nathaniel Clyne comes in to replace the 29-year-old, with Palace’s official website stating that Munoz is ‘nursing a minor knee injury’.
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The south London club will be hopeful to have Munoz back for next weekend’s league clash wih Manchester City.
Elsewhere, Ismaila Sarr remains absent with an ankle injury that he sustained in the 2-1 defeat to Manchester United last month.
Daniel Munoz has scored three goals in the Premier League this season (Picture: Getty)
Eddie Nketiah starts in place of the Senegal winger in a front three that also includes Yeremy Pino and Jean-Philippe Mateta.
Daichi Kamada, therefore, moves back into midfield to partner Adam Wharton, with Jefferson Lerma dropping to the bench.
Fulham, meanwhile, are without Ryan Sessegnon after he sustained a hamstring injury on Saturday, with Timothy Castagne coming in at left-back to replace the Englishman.
Samuel Chukwueze also gets an opportunity from the start after his two-goal cameo against City, replacing Sasa Lukic, who drops to the bench.
Fulham currently sit 15th in the table and have not beaten Palace at home since January 2005.
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