Billionaire who injected son’s blood plasma to live forever has incurable disease

Bryan Johnson, founder and chief executive officer of Kernel Holding SA, during the Milken Institute Global Conference in Beverly Hills, California, U.S., on Wednesday, Oct. 20, 2021. The event brings together individuals with the capital, power, and influence to change the world and connects them with those whose expertise and creativity are reinventing health, finance, technology, philanthropy, industry, and media. Photographer: Kyle Grillot/Bloomberg via Getty Images
Bryan Johnson has spent several years trying to age backwards and cheat death (Picture: Bloomberg via Getty Images)

Billionaire biohacker Bryan Johnson, the man determined to live forever, has revealed he has an incurable autoimmune disease.

The American entrepreneur, 48, has made headlines for his outlandish anti-ageing techniques, spending millions of dollars in a bid to extend his life and reduce his biological age to that of an 18-year-old.

Johnson refers to his Benjamin Button-esque ways as ‘Project Blueprint’, meticulously taking 54 supplements a day, eating every meal between 6am and 11.30am, and following a strict exercise regimen.

In 2023, he even underwent six monthly one-litre plasma transfusions, one of which was donated by his son.

Despite his efforts, Johnson has now discovered that immortality may not be in reach.

‘Bad news #1: I have an autoimmune disease. My stomach is eating itself,’ he wrote on social media. ‘Bad news #2: 2–5% of people have this, too. Likely more, because it hides.’

Bryan Johnson: Don't Die: The Man Who Wants to Live Forever. CREDIT: Courtesy of Netflix
The tech billionaire has, 48, has been trying to reduce the biological age of his organs to that of an 18-year-old (Picture: Netflix)

Johnson was unaware of his condition, but he is now trying to find a cure. Currently, it only has treatments to manage its symptoms.

‘I’m going to try and solve it. Will share all,’ he promised.

In his lengthy X post, he explained that, as a child, he ‘gobbled down fast food’ and consumed sugary drinks.

After ‘a few healthy years’ in his 20s, he found that ‘juggling the stress and grind’ of building a business and becoming a father saw his health ‘slip’.

‘Within a few years, I’d fallen into a deep, chronic depression.’

‘Somewhere in that timeline, my body began developing an autoimmune process affecting my thyroid and then my stomach lining,’ he added, sharing the condition’s name, called autoimmune gastritis (AIG).

Bryan Johnson at Keynote "Don't Die with Bryan Johnson" during SXSW Conference & Festivals at Austin Convention Center on March 13, 2025 in Austin, Texas. (Photo by Hubert Vestil/SXSW Conference & Festivals via Getty Images) 15884177
Biohacker Johnson has been told that his stomach is ‘eating itself’ (Picture: Hubert Vestil/SXSW Conference & Festivals via Getty Images)

After being diagnosed with hypothyroidism (an underactive thyroid) at 21, which he ‘successfully managed with common treatments for nearly three decades’, Johnson noticed signs that ‘something else was going on’.

But it was only in May this year that he was told of his AIG, a chronic, immune-mediated, inflammatory condition.

‘I’m unsure how long I’ve had it. AIG causes irreversible damage: nutritional deficiency, anaemia, and over a long horizon, elevated cancer risk,’ Johnson wrote.

In retrospect, he attributes various matters to the condition, such as low ferritin (a protein that stores iron) levels for 11 years. However, he did not have anaemia, and when continuously trying to raise his iron levels with food and vitamins, ‘nothing would work’.

He found that such issues were ‘explained away’ while other stones were left ‘unturned’.

The businessman went on in his post, saying he only received a diagnosis when he ‘overhauled’ his personal medical team to ‘lay the groundwork’ for a $1million-per-year longevity scheme called ‘Immortals Care’.

What is autoimmune gastritis (AIG)?

According to the Global Autoimmune Institute, it’s estimated that 0.5%-4.5% of adults worldwide have autoimmune gastritis.

It is a chronic, inflammatory condition of the stomach lining. The body’s antibodies attack the acid-producing cells that make up the stomach lining.

The condition can go untreated or be misdiagnosed since its symptoms tend to be non-specific. In many cases, a formal diagnosis isn’t made until later on.

‘With greater capacity, we revisited everything.’

He underwent numerous tests, including a colonoscopy, which, to his ‘surprise’, came back clear. He called his colon ‘perfectly healthy’ and the results ‘better than 95% of colonoscopies of men, according to the gastroenterologist’.

‘That ruled out the first concern and worst possible outcome: slow continuous bleeding from colon cancer, or pre-cancerous polyp.’

Then, a bi-directional endoscopy, a procedure that examines the entire intestinal tract as well as blood biomarkers, raised concerns of elevated levels of anti-parietal-cell antibodies, which are an indicator of AIG.

Subsequently, a stomach biopsy revealed his stomach had a weakened lining, confirming his autoimmune disease.

Still, the man who wants to cheat death remains optimistic, adding that he and his team are going to monitor his condition closely and perform additional tests to further understand AIG.

Emphasising that there is not a cure right now, he believes it can be found.

**BRIGHTENED** 13272285 Multi-millionaire biohacker Bryan Johnson reveals how he transformed his 'terrible' sleeping habits - as he claims getting more rest at night has helped to take YEARS off his age. Johnson says that sleep does not solve everything, but it provides the body with enough energy to accomplish what is needed to live longer. This includes exercising hard and eating less. Each week he gets 1 hour and 7 minutes of light exercise, 4 hours and 37 minutes of moderate exercise, and 1 hour and 25 minutes of vigorous exercise. Exercise, especially bouts of high-intensity vigorous exercise, is perhaps the most potent antidote to aging.
From sleep tracking to meticulous calorie control, Johnson lives a very regimented life (Picture: YouTube/Bryan Johnson)

‘Modern medicine has normalised too many conditions that erode our health, function, and comfort, shrinking the goal to monitoring and management while a cure is rarely even attempted,’ his essay concluded.

‘Most of these verdicts were handed down decades ago, in an era that predates nearly all of our current tech and science, and they have gone largely unchallenged.

‘We want to change that. In the age of AI, multiomics, and custom-built DNA, proteins, and cells, no condition should be presumed incurable simply because no one has yet tried to cure it with today’s stack.’

He signed off on a more personal note, reminding his followers how health can be ‘easily forgotten’ in the ‘noise’ of everyday life.

‘I wish all of you the very best. Care for yourself, care for others, care for the planet and care for our animal friends. Care for life as it’s the most precious gift there is.’

What has Bryan Johnson done to try to live forever?

13329485 Biohacker Bryan Johnson reveals why eating CHOCOLATE every day is ultimate secret to aging backward
He believes he and his medical team will find a cure for AIG (Picture: YouTube/Bryan Johnson)

The founder and former CEO of Kernel, a company creating devices to monitor and record brain activity, has fascinated the internet with his investments in trying not to die.

He spends roughly $2m (£1.5m) a year on his anti-ageing protocols, including his medical staff, tests, treatments, and therapies.

With a strict vegan diet, he eats approximately 1,977 calories a day in a compressed window (the recommended average daily amount is 2,500 calories a day for men), curating his intake based purely on biomarker data, not taste or preference.

He goes to bed at 8:30pm, during which period he tracks his sleep quality and other medical data and has regular MRIs and ultrasounds, overseen by around 30 hired physicians.

Does science support it?

Of course, several elements of Johnson’s lifestyle are scientifically supported for basic healthy living – objectively. These include a consistent sleep schedule, daily physical activity, stress management, and calorie control.

However, his more experimental efforts, such as injections and other therapies, are not yet scientifically supported.

Johnson has also been criticised by experts, who say that science may not yet be capable of providing the results he is seeking.

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