Saka and Timber have missed the Gunners last two games since the end of the international break with injuries.
While Mikel Arteta teased some of his injured players could return today, the duo have not been passed fit and are not included in the matchday squad.
Ben White continues at right-back with Noni Madueke ahead of him in attack.
Odegaard is also not in the squad despite arriving with the group at the Emirates on Saturday morning.
The captain started both games against Southampton and Sporting CP in the FA Cup and Champions League respectively but was forced off in the latter with 20 minutes remaining.
Norway manager Stale Solbakken this week revealed his international captain had suffered a ‘minor setback’ in training.
Substitutes: Arrizabalaga, Mosquera, Hincapie, Norgaard, Eze, Dowman, Trossard, Salmon, Jesus
There is also no room for Riccardo Calafiori in the squad.
The Italy international is another nursing an injury issue and with Piero Hincapie only deemed fit enough for the bench, there is a rare start for Myles Lewis-Skelly at left-back.
The Hale End graduate has only started one other Premier League match this season will the Gunners prepared to listen to offers for the 19-year-old at the end of the season.
Eberechi Eze is back among the subs after his recent knock.
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